β3-adrenoceptor agonist prevents alterations of muscle diacylglycerol and adipose tissue phospholipids induced by a cafeteria diet

Nutrition & Metabolism

Table 3 Composition of adipose tissue lipids

% mole fatty acids	REF	CAF	CAF-ZD
Phospholipids
Myristic acid (14:0)	3.04 ± 0.16	3.81 ± 0.19 *	2.96 ± 0.15 ++
Palmitic acid (16:0)	28.70 ± 3.10	30.72 ± 1.83	26.22 ± 1.70
Stearic acid (18:0)	15.99 ± 1.19	16.10 ± 0.75	16.93 ± 0.50
Palmitoleic acid (16:1n-7)	1.17 ± 0.28	1.35 ± 0.31	1.16 ± 0.29
Oleic acid (18:1n-9)	10.74 ± 0.94	18.17 ± 1.60 **	16.26 ± 1.39 *
Vaccenic acid (18:1n-7)	1.24 ± 0.12	0.89 ± 0.07 *	0.98 ± 0.10
Linoleic acid (18:2n-6)	21.21 ± 1.98	13.27 ± 1.20 **	16.41 ± 1.55 *
Eicosadienoic acid (20:2n-6)	2.16 ± 1.37	0.92 ± 0.92	0.37 ± 0.37
Arachidonic acid (20:4n-6)	7.69 ± 0.73	4.47 ± 1.23 *	8.90 ± 1.35 +
Triacylglycerol
Myristic acid (14:0)	1.23 ± 0.03	1.33 ± 0.08	1.39 ± 0.28
Palmitic acid (16:0)	21.80 ± 0.29	21.48 ± 0.63	21.02 ± 0.65
Stearic acid (18:0)	3.35 ± 0.15	5.27 ± 0.35 **	4.84 ± 1.68 *
Palmitoleic acid (16:1n-7)	2.50 ± 0.27	2.29 ± 0.34	2.44 ± 0.46
Oleic acid (18:1n-9)	24.37 ± 1.04	48.87 ± 1.35 **	47.09 ± 0.20 **
Vaccenic acid (18:1n-7)	1.98 ± 0.12	1.59 ± 0.12	1.73 ± 1.20
Linoleic acid (18:2n-6)	38.22 ± 1.36	16.59 ± 0.72 **	18.37 ± 0.16 **
α-linolenic acid (18:3n-3)	2.85 ± 0.16	0.67 ± 0.06 **	0.71 ± 0.20 **

Data are the mean ± SEM. Values significantly different from those obtained in the group of rats fed a chow diet (REF) are indicated by * (p < 0.05) and ** (p < 0.01). Data measured in the group of rats treated with ZD7114 (CAF-ZD) and significantly different from those in the group of rats fed a cafeteria diet (CAF) are shown by + (p < 0.05) and ++ (p < 0.05). Only main fatty acids are presented. CAF-ZD: rats fed a cafeteria diet and treated with ZD7114.