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Table 4 Effect of LC-MUFAs on body weight, body fat contents and plasma metabolites in KK-A y mice for 8 wk

From: Dietary supplementation with long-chain monounsaturated fatty acids attenuates obesity-related metabolic dysfunction and increases expression of PPAR gamma in adipose tissue in type 2 diabetic KK-Ay mice

 

Soybean oil diet (Control)

LC-MUFA diet

Food intake (g/day)

4.4 ± 0.3

4.4 ± 0.2

Initial body mass (g)

29.9 ± 0.4

29.5 ± 0.5

Final body mass (g)

42.4 ± 0.8

40.1 ± 1.1

Epididymal WAT (g/100 g BW)

4.6 ± 0.2

4.1 ± 0.2*

Mesenteric WAT (g/100 g BW)

2.7 ± 0.1

2.4 ± 0.1

Subcutaneous WAT(g/100 g BW)

3.2 ± 0.3

2.2 ± 0.2**

Body fat contents (g/100 g BW)

10.5 ± 0.4

8.8 ± 0.3**

Liver (g/100 g BW)

4.0 ± 0.1

4.8 ± 0.2*

Hepatic triglyceride (mg/g Liver)

60.5 ± 4.8

68.7 ± 2.7

Hepatic total cholesterol (mg/g Liver)

4.0 ± 0.6

3.8 ± 0.4

Plasma total cholesterol (mg/dL)

180.4 ± 7.3

156.4 ± 8.2*

Plasma triglycerides (mg/dL)

204.4 ± 13.5

220.4 ± 21.3

Plasma FFAs (μEq/mL)

696.4 ± 25

553.8 ± 30.7**

Plasma glucose (mg/dL)

486.4 ± 30.1

475.6 ± 42.3

Plasma insulin (ng/mL)

82.8 ± 8.9

61 ± 4.1*

Plasma leptin (ng/mL)

19.4 ±0.7

16.3 ±0.7*

  1. Each value represents the mean ± SE (n = 10). BW: body weight; FFAs: free fatty acids; WAT: white adipose tissue; Body fat contents: (epididymal adipose tissue + mesenteric adipose tissue + subcutaneous adipose tissue)/body weight. * p < 0.05; ** p < 0.01 compared with the control group.