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Table 6 Effect of LC-MUFAs on fatty acid composition (%) in mesenteric and subcutaneous WAT in KK-A y mice

From: Dietary supplementation with long-chain monounsaturated fatty acids attenuates obesity-related metabolic dysfunction and increases expression of PPAR gamma in adipose tissue in type 2 diabetic KK-Ay mice

Fatty acid

Mesenteric WAT

Subcutaneous WAT

Soybean oil diet (control)

LC-MUFA diet

Soybean oil diet (control)

LC-MUFA diet

14:0

0.81 ± 0.02

1.18 ± 0.02*

0.76 ± 0.09

1.31 ± 0.15* *

16:0

18.92 ± 0.27

20.97 ± 0.41**

15.42 ± 0.22

16.29 ± 0.98

18:0

2.31 ± 0.21

2.26 ± 0.09

1.45 ± 0.38

1.18 ± 0.42

20:0

0.10 ± 0

0.11 ± 0.01

0.08 ± 0

0.12 ± 0.01

SFA

22.13 ± 0.37

24.53 ± 0.43**

17.72 ± 0.31

18.90 ± 0.43

16:1 n-7

4.42 ± 0.21

5.24 ± 0.41

6.27 ± 0.89

7.27 ± 1.54

18:1 n-9

31.19 ± 0.39

35.68 ± 0.45***

30.06 ± 0.64

35.88 ± 0.85***

18:1 n-7

2.46 ± 0.13

3.03 ± 0.05**

2.64 ± 0.20

2.99 ± 0.39*

20:1 n-11

0.08 ± 0

3.03 ± 0.11***

0.05 ± 0

3.14 ± 0.32***

20:1 n-9

0.56 ± 0.01

1.27 ± 0.04***

0.48 ± 0.04

1.29 ± 0.09***

22:1 n-11

ND

1.29 ± 0.06***

ND

1.36 ± 0.19***

22:1 n-9

0.04 ± 0

0.13 ± 0.01***

0.03 ± 0

0.14 ± 0.02***

LC-MUFA

0.68 ± 0.01

5.72 ± 0.21***

0.57 ± 0.01

5.94 ± 0.19***

MUFA

38.63 ± 0.49

49.67 ± 0.91***

39.54 ± 0.38

52.07 ± 0.71***

18:2 n-6

33.58 ± 0.52

20.14 ± 0.52***

33.89 ± 0.98

19.62 ± 1.69***

18:3 n-6

0.05 ± 0

0.04 ± 0.01

0.06 ± 0

0.07 ± 0.01*

20:2 n-6

0.13 ± 0

0.09 ± 0.01***

0.11 ± 0.01

0.08 ± 0.01***

20:3 n-6

0.05 ± 0

0.04 ± 0*

0.06 ± 0

0.04 ± 0.01**

20:4 n-6

0.11 ± 0.01

0.09 ± 0.01

0.13 ± 0.01

0.09 ± 0.02***

n-6 PUFA

33.92 ± 0.52

18.37 ± 0.71***

34.26 ± 0.31

19.91 ± 0.63***

18:3 n-3

2.09 ± 0.22

1.09 ± 0.05**

2.64 ± 0.14

1.19 ± 0.10***

20:5 n-3

0.03 ± 0

0.01 ± 0.01

0.02 ± 0.01

0.03 ± 0.01

22:5 n-3

0.01 ± 0

0.01 ± 0

0.01 ± 0.01

0.02 ± 0.01

22:6 n-3

0.04 ± 0

0.14 ± 0.01***

0.04 ± 0.01

0.14 ± 0.02***

n-3 PUFA

2.16 ± 0.22

1.12 ± 0.14***

2.72 ± 0.05

1.38 ± 0.04***

n-3/n-6

0.06 ± 0.01

0.06 ± 0

0.08 ± 0

0.07 ± 0

  1. Each value represents the mean ± SE (n = 10). ND: Not detected; WAT: white adipose tissue; SFA: saturated fatty acids; MUFA: monounsaturated fatty acids; LC-MUFA: long-chain monounsaturated fatty acids (C20:1 and C22:1 isomers combined); PUFA: polyunsaturated fatty acids; * p < 0.05; ** p < 0.01; *** p < 0.001 compared with the control group.