Phenolic compounds from Rosemary (Rosmarinus officinalis L.) attenuate oxidative stress and reduce blood cholesterol concentrations in diet-induced hypercholesterolemic rats

Table 3 Weight gain, food intake, food efficiency ratio (FER) and lipid profile of the experimental groups

	C	HC	AQ 70	AQ 140	NEPF 7	NEPF 14
Weight Gain (g)	167.64 ± 13.41	179.21 ± 24.13ª	175.95 ± 16.22ª	174.06 ± 25.68ª	175.53 ± 17.75ª	179.67 ± 24.71ª
Food intake (g/day)	20.24 ± 2.82	21.85 ± 3.77ª	21.52 ± 3.38ª	21.32 ± 3.20ª	21.79 ± 3.53ª	22.05 ± 4.63ª
FER	0.38	0.37	0.37	0.37	0.37	0.39
TC (mg/dL)	61.30 ± 6.46	178.54 ± 33.31ª^*	107.47 ± 32.42^b	128.85 ± 23.71^ab	139.01 ± 38.25^a	143.01 ± 37.92^a
Non-HDL-c (mg/dL)	26.46 ± 1.76	152.00 ± 14.67ª^*	84.47 ± 12.78^b	103.70 ± 10.03^ab	120.60 ± 17.46^a	127.20 ± 18.59^a
HDL-c (mg/dL)	38.15 ± 6.49	21.36 ± 3.47ª^*	25.04 ± 2.57ª	25.28 ± 2.24ª	21.42 ± 3.71ª	21.04 ± 2.10ª
TG (mg/dL)	25.34 ± 7.75	30.25 ± 7.76ª	26.25 ± 5.28ª	23.92 ± 4.68ª	26.13 ± 4.57ª	30.27 ± 4.63ª

C (normocholesterolemic group), HC (hypercholesterolemic group), AQ 70 (HC + aqueous extract 70 mg/kg), AQ 140 (HC + aqueous extract 140 mg/kg), NEPF 7 (HC + non-esterified phenolic fraction 7 mg/kg), NEPF 14 (HC + non-esterified phenolic fraction 14 mg/kg).
The results are expressed as the means ± S.E.M (n = 5-8).
Different letters represent significant differences between rows (Tukey-Kramer test, p < 0.05), * significant difference between normocholesterolemic (C) vs hypercholesterolemic (HC) groups by Student’s t test (p < 0.05).

ISSN: 1743-7075