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Table 2 Baseline and 3 months plasma antioxidants and markers of oxidative damage in the intervention group compared with the placebo group (mean SD)

From: Oxidative damage and inflammation in obese diabetic Emirati subjects supplemented with antioxidants and B-vitamins: a randomized placebo-controlled trail

   Placebo Supplement B (95% C.I) + P value*
(n = 50) (n = 50)
Vitamin C (mg/l) Baseline 23.8 (16.8) 33.00 (20.1)   
  3 months 19.5 (12.1) 18.9 (12.8) −0.3 (−6.5, 5.8) 0.913
Vitamin E (mg/l) baseline 7.3 (4.5) 8.6 (3.2)   
  3 months 7.6 (4.6) 11.4 (4.5) 3.1 (0.9, 5.3) 0.006
Vitamin A (mg/l) Baseline 0.578 (0.29) 0.797 (0.34)   
  3 months 0.624 (0.39) 0.844 (0.29) 0.1(−0.12, 0.22) 0.541
Glutathione(nM/ml) Baseline 0.231 (0.27) 0.245 (0.31)   
  3 months 0.139 (0.13) 0.169 (0.15) 0.03 (−0.04, 0.10) 0.346
Folate (nmol/l) baseline 18.2 (8.9) 18.95 ((8.1)   
  3 months 18.7 (8.6) 32.4 (11.9) 13.5 (9.7, 17.4) 0.001
B12 (pmol/l) Baseline 236 (103) 179 (93)   
  3 months 227 (99) 252 (191) 93 (48, 139) 0.001
Homocysteine Baseline 10.3 (3.2) 12.7 (4.5)   
(mmol/l) 3 months 10.7 (3.3) 11.5 (3.3) −0.33 (−1.8, 1.2) 0.657
Protein carbonyl baseline 0.797 (0.28) 0.456 (0.46)   
(nmol/mg) 3 months 1.080 (0.46) 0.737 (0.35) −0.34 (−0.56, -0.13 0.002
MDA (nM/ml) Baseline 16.7 (15.8) 6.1 (8.9)   
  3 months 18.5 (9.9) 19.7 (11.2) −0.64 (−5.96, 4.67) 0.810
  1. * 3 months values were regressed on baseline values and intervention (placebo 1/supplement 2).
  2. + B = regression coefficient (95% confidence interval).