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Figure 3 | Nutrition & Metabolism

Figure 3

From: Supplementation of carnitine leads to an activation of the IGF-1/PI3K/Akt signalling pathway and down regulates the E3 ligase MuRF1 in skeletal muscle of rats

Figure 3

(A) Relative mRNA abundance of IGF-1 in liver of rats fed either a control diet (0 mg carnitine/ kg diet; Control) or a diet supplemented with 1250 mg carnitine/ kg diet (Carnitine) . Bars are means ± SD (n = 12/group). The normalized expression ratio in the control group is set to 1.0. * indicates a significant difference to the control group (P < 0.05). (B) Concentration of IGF-1 (ng/ml) in plasma of rats fed either a control diet (0 mg carnitine/kg diet; Control) or a diet supplemented with 1250 mg carnitine/kg diet (Carnitine). Bars represent mean ± SD (n = 12/group). * indicates a significant difference to the control group (P < 0.05).

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Nutrition & Metabolism

ISSN: 1743-7075

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