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Figure 5 | Nutrition & Metabolism

Figure 5

From: Fructose-induced stress signaling in the liver involves methylglyoxal

Figure 5

Stress and insulin signaling in primary hepatocytes. Phosphorylation of MKK7, JNK, serine 307 of IRS-1 and tyrosine phosphorylation of IRS-1 and IRS-2 in primary hepatocytes in response to methylglyoxal in the absence (A) or presence (B) of insulin. Data in graphs are the mean ± SDEV for 6 independent experiments performed in triplicate. * significantly different from No Additions (p < 0.05).

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