Circulating glucagon-like peptide-1 increases in response to short-term overfeeding in men

Nutrition & Metabolism

Table 4 Spearman correlations of baseline variables related to change in fasting serum GLP-1 concentration ^a,b

	All subjects (n = 72)		Normal weight (n = 30)		Overweight+Obese (n = 42)
	r	P	r	P	r	P
Weight (kg)	0.251	0.033	0.391	0.033	0.162	NS
BMI (kg/m²)	0.295	0.012	0.446	0.013	0.188	NS
Percent body fat	0.130	NS	0.272	NS	0.109	NS
Percent trunk fat	0.139	NS	0.307	NS	0.104	NS
Percent android fat	0.127	NS	0.278	NS	0.077	NS
Percent gynoid fat	0.068	NS	0.239	NS	−0.074	NS
Total cholesterol	−0.112	NS	−0.255	NS	−0.030	NS
HDL cholesterol	−0.085	NS	−0.291	NS	0.095	NS
Total cholesterol:HDLc ratio	−0.012	NS	0.066	NS	−0.082	NS
LDL cholesterol	−0.118	NS	−0.179	NS	−0.115	NS
Triacylglycerols	−0.151	NS	−0.226	NS	−0.110	NS
Glucose	0.016	NS	−0.122	NS	0.124	NS
Insulin	0.135	NS	0.079	NS	0.074	NS
HOMA-IR	0.135	NS	0.059	NS	0.083	NS
HOMA-β	0.158	NS	0.248	NS	0.063	NS
GLP-1	−0.416	<0.001	−0.484	0.007	−0.396	0.009

^a P<0.05 (IBM SPSS Statistics 19).
^b Homeostasis model assessment of insulin resistance (HOMA-IR) and of β cell function (HOMA-β); NS, non-significant. Subjects were classifed based on adiposity recommendations by Bray as normal weight (8–20.9%), overweight (21–25.9%), or obese (>26%).

ISSN: 1743-7075