Effects of Lactobacillus reuteri GMNL-263 on hepatic steatosis in treated rats. At the end of the experimental period (14 weeks), the livers obtained from sacrificed rats were subjected to hematoxylin and eosin staining for evaluation of hepatic steatosis. The histological sections of rat liver were observed at magnification 200 ×. (A) Liver section from control rat showed normal appearance of liver cells; (B) Liver section from high-fructose-diets fed rats showed marked fatty infiltration of hepatocytes with macro- or micro-vesicular steatosis (black arrow); (C) Liver section from Lactobacillus reuteri GMNL-263 and high fructose-treated rats showed mild fatty infiltration of hepatocytes (black arrow). The result shown here was from one representative experiment of six different samples with similar results.