High fat | Low fat | Low fat + n-3 | ||
---|---|---|---|---|
n = 17 | n = 16 | n = 17 | p-value2 | |
18:2n6 | ||||
Baseline | 280.69 ± 14.57 | 284.66 ± 14.76 | 293.95 ± 14.59 | 0.41 |
8 weeks | 285.49 ± 12.54a | 269.21 ± 12.86a | 233.08 ± 12.59b* | 0.0006 |
Δ 8 weeks | 4.81 ± 10.90a | −16.08 ± 11.29a | −60.85 ± 10.95b | 0.0001 |
p-value3 | 0.66 | 0.16 | < 0.0001 | |
18:3n3 | ||||
Baseline | 4.00 ± 0.86 | 4.51 ± 0.88 | 3.22 ± 0.86 | 0.34 |
8 weeks | 2.57 ± 0.45a | 3.12 ± 0.47a | 6.85 ± 0.45b* | < 0.0001 |
Δ 8 weeks | −1.43 ± 0.79a | −1.30 ± 0.82a | 3.62 ± 0.79b | < 0.0001 |
p-value3 | 0.08 | 0.12 | < 0.0001 | |
20:4n6 | ||||
Baseline | 120.62 ± 7.83 | 121.51 ± 7.94 | 126.04 ± 7.84 | 0.59 |
8 weeks | 107.89 ± 7.14a* | 135.62 ± 7.34b* | 100.12 ± 7.17a* | 0.0001 |
Δ 8 weeks | −12.72 ± 5.13a | 13.47 ± 5.33b | −25.90 ± 5.16a | < 0.0001 |
p-value3 | 0.02 | 0.02 | < 0.0001 | |
20:5n-3 | ||||
Baseline | 11.43 ± 1.77 | 11.80 ± 1.82 | 9.69 ± 1.78 | 0.49 |
8 weeks | 6.89 ± 1.80a* | 9.99 ± 1.87a | 29.86 ± 1.81b* | < 0.0001 |
Δ 8 weeks | −4.54 ± 1.94a | −1.91 ± 2.02a | 20.17 ± 1.96b | < 0.0001 |
p-value3 | 0.02 | 0.35 | < 0.0001 | |
22:5n-3 | ||||
Baseline | 9.94 ± 0.78 | 10.56 ± 0.79 | 10.72 ± 0.78 | 0.49 |
8 weeks | 8.41 ± 0.88a* | 11.04 ± 0.91b | 13.45 ± 0.89c* | < 0.0001 |
Δ 8 weeks | −1.52 ± 0.69a | 0.36 ± 0.72a | 2.73 ± 0.70b | < 0.0001 |
p-value3 | 0.03 | 0.62 | 0.0003 | |
22:6n-3 | ||||
Baseline | 30.18 ± 2.82 | 28.90 ± 2.89 | 29.68 ± 2.83 | 0.89 |
8 weeks | 24.06 ± 3.77a* | 35.03 ± 3.90b* | 55.00 ± 3.78c* | < 0.0001 |
Δ 8 weeks | −6.12 ± 2.56a | 5.95 ± 2.65b | 25.32 ± 2.57c | < 0.0001 |
p-value3 | 0.02 | 0.03 | < 0.0001 | |
Total n-3 | ||||
Baseline | 59.71 ± 5.33 | 60.07 ± 5.42 | 56.75 ± 5.34 | 0.68 |
8 weeks | 44.50 ± 6.37a* | 62.86 ± 6.60b | 110.10 ± 6.41c* | < 0.0001 |
Δ 8 weeks | −15.21 ± 4.95a | 2.55 ± 5.14b | 54.36 ± 4.98c | < 0.0001 |
p-value3 | 0.004 | 0.62 | < 0.0001 | |
Total n-6 | ||||
Baseline | 452.87 ± 21.30 | 456.78 ± 21.57 | 468.55 ± 21.34 | 0.53 |
8 weeks | 432.99 ± 18.17a | 458.41 ± 18.74a | 370.63 ± 18.25b* | 0.0005 |
Δ 8 weeks | −19.85 ± 14.82a | −0.58 ±15.34a | −97.85 ± 14.89b | < 0.0001 |
p-value3 | 0.19 | 0.97 | < 0.0001 |