Figure 4

Correlations between plasma PCSK9 levels (ng/ml) and (A) glucose infusion rate (GIR) during the 1st step of hyperinsulinemic-euglycemic clamp (mg/kg/min), (B) hepatic glucose production (HGP) during the 1st step of hyperinsulinemic-eugyclemic clamp (mg/kg/min), (C) intrahepatocellular lipid content (IHCL)(mmol/kg), and (D) VLDL-TG (mmol/l) in healthy volunteers (n=7) and OffT2D subjects (n=15) under a HFruc diet. Correlations were made using Spearman’s correlation test.