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Table 4 Plasma and muscle ( M. rectus femoris ) concentrations of carnitine, plasma concentrations of TG and NEFA and liver concentration of TG in lean rats (lean control), obese Zucker rats fed a control diet (obese control) or obese Zucker rats fed a diet supplemented with 3 g/kg diet carnitine (obese carnitine) for 4 wk 1

From: Carnitine supplementation to obese Zucker rats prevents obesity-induced type I to type II muscle fiber transition and favors an oxidative phenotype of skeletal muscle

  Lean Obese Obese
control control carnitine
Plasma (μmol/l)
 Total carnitine 62.3 ± 1.9b 40.0 ± 1.1c 90.5 ± 2.9a
 Free carnitine 50.8 ± 1.6b 33.7 ± 1.2c 73.2 ± 2.5a
 Acetyl-carnitine 11.5 ± 0.9b 6.3 ± 0.3c 17.3 ± 0.8a
M. rectus femoris (nmol/g)
 Total carnitine 919 ± 13b 752 ± 13c 1165 ± 19a
 Free carnitine 742 ± 12b 590 ± 9c 937 ± 21a
 Acetyl-carnitine 176 ± 4b 161 ± 4b 228 ± 6a
Plasma (mmol/l)
 TG 1.42 ± 0.06c 6.35 ± 0.18a 4.42 ± 0.26b
 NEFA 0.73 ± 0.06c 3.53 ± 0.16a 2.41 ± 0.18b
Liver (μmol/g)
 TG 10.2 ± 0.9b 87.7 ± 13.7a 65.6 ± 8.1a
  1. 1Data are expressed as means ± SEM, n = 12 rats/group. Means in a row without a common letter differ (P < 0.05).