Nutrition & Metabolism

Table 4 Plasma and muscle ( M. rectus femoris ) concentrations of carnitine, plasma concentrations of TG and NEFA and liver concentration of TG in lean rats (lean control), obese Zucker rats fed a control diet (obese control) or obese Zucker rats fed a diet supplemented with 3 g/kg diet carnitine (obese carnitine) for 4 wk ¹

From: Carnitine supplementation to obese Zucker rats prevents obesity-induced type I to type II muscle fiber transition and favors an oxidative phenotype of skeletal muscle

	Lean	Obese	Obese
	control	control	carnitine
Plasma (μmol/l)
Total carnitine	62.3 ± 1.9^b	40.0 ± 1.1^c	90.5 ± 2.9^a
Free carnitine	50.8 ± 1.6^b	33.7 ± 1.2^c	73.2 ± 2.5^a
Acetyl-carnitine	11.5 ± 0.9^b	6.3 ± 0.3^c	17.3 ± 0.8^a
M. rectus femoris (nmol/g)
Total carnitine	919 ± 13^b	752 ± 13^c	1165 ± 19^a
Free carnitine	742 ± 12^b	590 ± 9^c	937 ± 21^a
Acetyl-carnitine	176 ± 4^b	161 ± 4^b	228 ± 6^a
Plasma (mmol/l)
TG	1.42 ± 0.06^c	6.35 ± 0.18^a	4.42 ± 0.26^b
NEFA	0.73 ± 0.06^c	3.53 ± 0.16^a	2.41 ± 0.18^b
Liver (μmol/g)
TG	10.2 ± 0.9^b	87.7 ± 13.7^a	65.6 ± 8.1^a

¹Data are expressed as means ± SEM, n = 12 rats/group. Means in a row without a common letter differ (P < 0.05).

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ISSN: 1743-7075

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