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Table 6 Estimates of D9D activity according to genotype for each SCD1 SNP in Asians

From: Plasma concentration of cis 9trans 11 CLA in males and females is influenced by SCD1 genetic variations and hormonal contraceptives: a cross-sectional study

  [18:2c9t11/18:1 t11] in males [18:2c9t11/18:1 t11] in females
MM Mm mm P-value MM Mm mm P-value
rs10883463 1.039 ± 0.041 0.813 ± 0.064 - 0.46 1.085 ± 0.027 0.783 - 0.23
rs17669878 1.094 ± 0.059 0.966 ± 0.052 0.910 ± 0.118 0.18 1.035 ± 0.035 1.139 ± 0.043 1.061 ± 0.096 0.28
rs2060792 0.949 ± 0.049 1.052 ± 0.064 1.185 ± 0.107 0.27 1.090 ± 0.040 1.058 ± 0.038 1.185 ± 0.084 0.37
rs3071 1.069 ± 0.061 0.959 ± 0.048 1.103 ± 0.121 0.34 1.052 ± 0.038 1.143 ± 0.041 0.939 ± 0.063 0.11
rs3793766 1.035 ± 0.047 1.053 ± 0.081 0.752 ± 0.036 0.88 1.072 ± 0.030 1.117 ± 0.056 0.906 ± 0.081 0.59
rs3793767 0.993 ± 0.057 1.028 ± 0.058 1.120 ± 0.104 0.66 1.109 ± 0.044 1.051 ± 0.037 1.120 ± 0.067 0.54
rs490726 1.035 ± 0.048 1.070 ± 0.077 0.795 ± 0.051 0.68 1.056 ± 0.034 1.128 ± 0.044 1.038 ± 0.101 0.19
rs522951 0.975 ± 0.053 1.030 ± 0.062 1.164 ± 0.102 0.40 1.095 ± 0.041 1.058 ± 0.038 1.156 ± 0.080 0.42
rs569184 1.041 ± 0.049 1.052 ± 0.076 0.807 ± 0.064 0.86 1.045 ± 0.034 1.129 ± 0.046 1.070 ± 0.093 0.25
rs575338 N/A     1.082 ± 0.027 0.815 ± 0.143 - 0.47
  1. Results of analysis of 10 SNPs from SCD1 for associations with D9D activity index [182c9t11:181 t11]. P-values were determined using linear regression models which were adjusted for BMI, age, % of Total Energy from Dietary Fat and physical activity. Caucasian Males: n = 113; Caucasian females: n = 298; Asian Males: n = 98; Asian Females: n = 277. Abbreviations: D9D, delat-9-desaturase; M, major; m, minor; na, not applicable; ‘-’ indicates that no subjects with this genotype were present in this population.