Effect of GSPs on oral glucose tolerance in normal and diabetic rats. Plasma glucose response during the oral glucose tolerance test procedure in normal and diabetic rats was determined at the end of 1 (A) and 16 (B) week after induction of diabetes. Values were obtained for each group of 6 animals. Group a = vehicle-treated normal rats; group b = GSPs (250 mg/kg BW)-treated normal rats; group c = vehicle-treated diabetic rats; group d = GSPs (125 mg/kg BW)-treated diabetic rats; group e = GSPs (250 mg/kg BW)-treated diabetic rats; and group f = GSPs (500 mg/kg BW)-treated diabetic rats. * P < 0.05 versus data from vehicle-treated normal rats, and # P < 0.05 versus data from vehicle-treated diabetic rats at the indicated times, respectively.