Table 1 Comparison of diet-induced thermogenesis (DIT) with FCCS vs isocaloric amounts of glucose
Study | Test meals | Participants | DIT glucose | DIT fructose | (DIT fructose/DIT glucose) X 100 | P value |
|---|---|---|---|---|---|---|
| Â | Â | Â | (% energy content of the meal) | (% energy content of the meal) | Â | Â |
Sharief et al., 1982 | 5 g sucrose or glucose/kg ideal body weight | 6 normal weight M mean age: not provided | 2.6 | 4.0 | 154 | NS |
Tappy et al., 1986 | 75 g pure fructose or glucose | 10 normal weight subjects (6M,4F) mean age: 27 y | 6.5 | 10.2 | 157 | <0.05 |
Simonson et al., 1988 | 75 g pure fructose or glucose | 9 normal weight subjects (5M, 4F) mean age: 25 y | 6.0 | 9.4 | 157 | NS |
Simonson et al., 1988 | 75 g pure fructose or glucose | 9 normal weight subjects (5M, 4F) mean age: 61 y | 3.4 | 10.3 | 303 | <0.05 |
Simonson et al., 1988 | 75 g pure fructose or glucose | 9 obese subjects (2M, 7F) mean age: 60 y | 2.6 | 8.6 | 331 | <0.05 |
Schwarz et al., 1989 | 75 g fructose or glucose in a test meal | 20 normal weight subjects (10M, 10F) mean age: 23 y (M); 23 y (F) | 10.7 | 12.4 | 116 | <0.01 |
Schwarz et al., 1992 | 75 g fructose or glucose added to a meal | 10 normal weight F and 13 overweight F mean age: 23 y (normal weight); 26 y (overweight) | 8.4 | 10.2 | 121 | <0.01 |
Martines et al., 1994 | 1g fructose or glucose/kg body weight | 6 normal weight M mean age: 35 y | 10.7 | 11.2 | 105 | NS |
Fukagawa et al., 1995 | 75 g pure fructose or glucose | 8 young, normal weight subjects (6M,2F) mean age: 21 y (M); 20 y (F) | 8.1 | 9.4 | 116 | NS |
Fukagawa et al., 1995 | 75 g pure fructose or glucose | 8 older, normal weight subjects (4M, 4F) mean age: 76 y (M); 71 y (F) | 6.5 | 7.7 | 118 | NS |
Blaak et al., 1996 | 75 g pure fructose or glucose | 10 young normal weight M mean age: 28 y | 8.0 | 11.1 | 139 | <0.017 |
Blaak et al., 1996 | 75 g pure sucrose or glucose | 10 young normal weight M mean age: 28 y | 8.0 | 11.4 | 143 | <0.017 |
Van Gaal et al., 1999 | 100 g pure fructose or glucose | 13 overweight F mean age: not provided | 4.5 | 6.8 | 152 | <0.006 |
Mean | Â | Â | 6.6 | 9.4 | 162 | Â |
(range) |  |  | (2.6-10.7) | (4–12.4) | (105–157) |  |