Skip to main content

Table 1 Comparison of diet-induced thermogenesis (DIT) with FCCS vs isocaloric amounts of glucose

From: Effects of fructose-containing caloric sweeteners on resting energy expenditure and energy efficiency: a review of human trials

Study Test meals Participants DIT glucose DIT fructose (DIT fructose/DIT glucose) X 100 P value
    (% energy content of the meal) (% energy content of the meal)   
Sharief et al., 1982 5 g sucrose or glucose/kg ideal body weight 6 normal weight M mean age: not provided 2.6 4.0 154 NS
Tappy et al., 1986 75 g pure fructose or glucose 10 normal weight subjects (6M,4F) mean age: 27 y 6.5 10.2 157 <0.05
Simonson et al., 1988 75 g pure fructose or glucose 9 normal weight subjects (5M, 4F) mean age: 25 y 6.0 9.4 157 NS
Simonson et al., 1988 75 g pure fructose or glucose 9 normal weight subjects (5M, 4F) mean age: 61 y 3.4 10.3 303 <0.05
Simonson et al., 1988 75 g pure fructose or glucose 9 obese subjects (2M, 7F) mean age: 60 y 2.6 8.6 331 <0.05
Schwarz et al., 1989 75 g fructose or glucose in a test meal 20 normal weight subjects (10M, 10F) mean age: 23 y (M); 23 y (F) 10.7 12.4 116 <0.01
Schwarz et al., 1992 75 g fructose or glucose added to a meal 10 normal weight F and 13 overweight F mean age: 23 y (normal weight); 26 y (overweight) 8.4 10.2 121 <0.01
Martines et al., 1994 1g fructose or glucose/kg body weight 6 normal weight M mean age: 35 y 10.7 11.2 105 NS
Fukagawa et al., 1995 75 g pure fructose or glucose 8 young, normal weight subjects (6M,2F) mean age: 21 y (M); 20 y (F) 8.1 9.4 116 NS
Fukagawa et al., 1995 75 g pure fructose or glucose 8 older, normal weight subjects (4M, 4F) mean age: 76 y (M); 71 y (F) 6.5 7.7 118 NS
Blaak et al., 1996 75 g pure fructose or glucose 10 young normal weight M mean age: 28 y 8.0 11.1 139 <0.017
Blaak et al., 1996 75 g pure sucrose or glucose 10 young normal weight M mean age: 28 y 8.0 11.4 143 <0.017
Van Gaal et al., 1999 100 g pure fructose or glucose 13 overweight F mean age: not provided 4.5 6.8 152 <0.006
Mean    6.6 9.4 162  
(range)    (2.6-10.7) (4–12.4) (105–157)