Figure 4

Lipid raft modifier methyl beta cyclodextrin (MβCD) decreases ex vivo endotoxin transport. A) Endotoxin transport and B) transepithelial resistance was measured using Ussing chambers in ileum tissues treated with either control (water), MβCD, coconut oil, or coconut oil plus MβCD. Tissue (n = 7 /trt) were pretreated with these treatments for 30 min before FITC-LPS transport was assessed. Different letters represent significant difference at P < 0.05. Data are means ± S.E.M.