Skip to main content

Table 3 Biliary lipid values in P2Y 13 +/+ (WT) and P2Y 13 -/- mice fed a HCD for 16 weeks

From: Lack of P2Y13 in mice fed a high cholesterol diet results in decreased hepatic cholesterol content, biliary lipid secretion and reverse cholesterol transport

 

WT

P2Y13-/-

Bile flow (μl/min/100 g BW)

5.58 ± 0.42

4.35 ± 0.26*

Cholesterol secretion (nmol/min/100 g BW)

3.79 ± 0.27

2.71 ± 0.36*

Bile acid secretion (nmol/min/100 g BW)

209.9 ± 16.0

167.1 ± 10.2*

Phospholipid secretion (nmol/min/100 g BW)

15.7 ± 0.2

9.7 ± 0.2*

  1. Values are expressed as means ± SEM; n = 10 mice per group.
  2. *Indicates significant difference (p < 0.05) from control mice.