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Table 3 Biliary lipid values in P2Y 13 +/+ (WT) and P2Y 13 -/- mice fed a HCD for 16 weeks

From: Lack of P2Y13 in mice fed a high cholesterol diet results in decreased hepatic cholesterol content, biliary lipid secretion and reverse cholesterol transport

  WT P2Y13-/-
Bile flow (μl/min/100 g BW) 5.58 ± 0.42 4.35 ± 0.26*
Cholesterol secretion (nmol/min/100 g BW) 3.79 ± 0.27 2.71 ± 0.36*
Bile acid secretion (nmol/min/100 g BW) 209.9 ± 16.0 167.1 ± 10.2*
Phospholipid secretion (nmol/min/100 g BW) 15.7 ± 0.2 9.7 ± 0.2*
  1. Values are expressed as means ± SEM; n = 10 mice per group.
  2. *Indicates significant difference (p < 0.05) from control mice.