Activation of transsulfuration pathway by salvianolic acid a treatment: a homocysteine-lowering approach with beneficial effects on redox homeostasis in high-fat diet-induced hyperlipidemic rats

Table 2 The methylation status in the liver

	Control	Control + Sal A	Hyperlipidemia	Hyperlipidemia + Sal A
SAM (nmol/g liver)	112.8 ± 10.8	83.0 ± 4.8^**	64.2 ± 5.0^***	60.3 ± 5.5
SAH (nmol/g liver)	26.7 ± 1.7	27.8 ± 1.4	27.9 ± 1.5	23.3 ± 1.6
SAM/SAH	4.2 ± 0.4	3.0 ± 0.2^**	2.4 ± 0.3^**	2.6 ± 0.3

Data are represented as means ± SEM, n = 6.
^*p < 0.05 (vs. control group). ^**p < 0.01 (vs. control group). ^***p < 0.001 (vs. control group).
^#p < 0.05 (vs. hyperlipidemia group). ^##p < 0.01 (vs. hyperlipidemia group). ^###p < 0.001 (vs. hyperlipidemia group).