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Table 1 The effect of melatonin administration on urea-N and creatinine levels in kidney of experimental rats (n=10)

From: Melatonin suppresses cisplatin-induced nephrotoxicity via activation of Nrf-2/HO-1 pathway

Item Groups
Control Melatonin Cisplatine Melatonin + Cisplatine
Urea-N (mg/dl) 31.5 ± 3.4c 30.9 ± 2.0c 438.9 ± 63.1a 209.0 ± 42.5b
Creatinine (mg/dl) 0.68 ± 0.19c 0.67 ± 0.14c 3.61 ± 0.43a 1.91 ± 0.57b
  1. Values are mean ± SE of 10 rats from each group. a, b, c: means in the same row not sharing a common superscript are significantly different (P< 0.05) between groups.