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Table 2 Effects of Control IgY (CY) and Anti-lipase IgY (AY) on physiological parameters

From: Anti-obesity activity of hen egg anti-lipase immunoglobulin yolk, a novel pancreatic lipase inhibitor

 

CY

AY

Initial body weight (g)

27.57 ± 0.27

22.50 ± 0.38

Final body weight (g)

26.18 ± 0.75

25.47 ± 1.01

Body weight gain (g/35 d)

3.61 ± 0.88

2.97 ± 0.85

Total food intake (g/35 d)

99.27 ± 4.81

95.28 ± 2.31

Fecal dry weight (g/3d)

0.96 ± 0.03

0.91 ± 0.02

Tissue weight (mg/g B.W.)

  

 Liver weight

33.6 ± 0.64

34.7 ± 1.07

 Epididymal WAT

26.8 ± 2.76

20.2 ± 0.40*

 Mesenteric WAT

9.32 ± 0.94

6.57 ± 0.50*

 Retroperitoneal WAT

14.0 ± 1.18

10.8 ±0.41*

 Perirenal WAT

9.51 ± 1.31

6.32 ± 0.40*

 Intraperitoneal WAT

59.6 ± 5.74

43.9 ± 0.73*

Tissue weight (mg)

  

 Liver weight

877.5 ± 22.6

877.6 ± 20.5

 Epididymal WAT

709.9 ± 87.3

513.5 ± 20.4*

 Mesenteric WAT

246.5 ± 29.9

169.0 ± 16.4*

 Retroperitoneal WAT

332.0 ± 53.1

273.3 ± 13.0*

 Perirenal WAT

251.6 ± 39.9

162.0 ± 13.5*

 Intraperitoneal WAT

1573.4 ± 180.5

1117.8 ± 52.0*

Plasma parameters

  

 Triglyceride (mg/dl)

54.2 ± 3.6

44.6 ± 3.9

 Cholesterol (mg/dl)

109.1 ± 3.9

104.6 ± 3.4

 Glucose (mg/dl)

134.7 ± 7.1

137.1 ± 7.2

 Insulin (ng/ml)

0.14 ± 0.02

0.14 ± 0.02

 TNF-α (pg/ml)

3.29 ± 0.12

3.66 ± 0.17

Liver lipids (mg/g liver)

  

 Total lipids

132.6 ± 10.8

90.6 ± 7.9**

 Triglyceride

51.9 ± 0.9

45.0 ± 2.6*

 Cholesterol

6.77 ± 0.45

4.32 ± 0.17**

Fecal lipids (mg/3d)

  

 Total lipids

71.4 ± 2.89

77.1 ± 2.48

 Triglyceride

5.67 ± 0.32

7.50 ± 0.64*

 Cholesterol

6.65 ± 0.35

6.72 ± 0.26

  1. 1. Each value is the mean ± SEM, n = 8.
  2. 2. Asterisks indicate significant differences as compared with mice fed a high-fat diet containing control IgY by Student’s t-test (*p < 0.05; **p < 0.01).
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Nutrition & Metabolism

ISSN: 1743-7075

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