Skip to main content

Table 2 Effects of Control IgY (CY) and Anti-lipase IgY (AY) on physiological parameters

From: Anti-obesity activity of hen egg anti-lipase immunoglobulin yolk, a novel pancreatic lipase inhibitor

  CY AY
Initial body weight (g) 27.57 ± 0.27 22.50 ± 0.38
Final body weight (g) 26.18 ± 0.75 25.47 ± 1.01
Body weight gain (g/35 d) 3.61 ± 0.88 2.97 ± 0.85
Total food intake (g/35 d) 99.27 ± 4.81 95.28 ± 2.31
Fecal dry weight (g/3d) 0.96 ± 0.03 0.91 ± 0.02
Tissue weight (mg/g B.W.)   
 Liver weight 33.6 ± 0.64 34.7 ± 1.07
 Epididymal WAT 26.8 ± 2.76 20.2 ± 0.40*
 Mesenteric WAT 9.32 ± 0.94 6.57 ± 0.50*
 Retroperitoneal WAT 14.0 ± 1.18 10.8 ±0.41*
 Perirenal WAT 9.51 ± 1.31 6.32 ± 0.40*
 Intraperitoneal WAT 59.6 ± 5.74 43.9 ± 0.73*
Tissue weight (mg)   
 Liver weight 877.5 ± 22.6 877.6 ± 20.5
 Epididymal WAT 709.9 ± 87.3 513.5 ± 20.4*
 Mesenteric WAT 246.5 ± 29.9 169.0 ± 16.4*
 Retroperitoneal WAT 332.0 ± 53.1 273.3 ± 13.0*
 Perirenal WAT 251.6 ± 39.9 162.0 ± 13.5*
 Intraperitoneal WAT 1573.4 ± 180.5 1117.8 ± 52.0*
Plasma parameters   
 Triglyceride (mg/dl) 54.2 ± 3.6 44.6 ± 3.9
 Cholesterol (mg/dl) 109.1 ± 3.9 104.6 ± 3.4
 Glucose (mg/dl) 134.7 ± 7.1 137.1 ± 7.2
 Insulin (ng/ml) 0.14 ± 0.02 0.14 ± 0.02
 TNF-α (pg/ml) 3.29 ± 0.12 3.66 ± 0.17
Liver lipids (mg/g liver)   
 Total lipids 132.6 ± 10.8 90.6 ± 7.9**
 Triglyceride 51.9 ± 0.9 45.0 ± 2.6*
 Cholesterol 6.77 ± 0.45 4.32 ± 0.17**
Fecal lipids (mg/3d)   
 Total lipids 71.4 ± 2.89 77.1 ± 2.48
 Triglyceride 5.67 ± 0.32 7.50 ± 0.64*
 Cholesterol 6.65 ± 0.35 6.72 ± 0.26
  1. 1. Each value is the mean ± SEM, n = 8.
  2. 2. Asterisks indicate significant differences as compared with mice fed a high-fat diet containing control IgY by Student’s t-test (*p < 0.05; **p < 0.01).