ApoC-III and visceral adipose tissue contribute to paradoxically normal triglyceride levels in insulin-resistant African-American women

Sumner, Anne E; Furtado, Jeremy D; Courville, Amber B; Ricks, Madia; Younger-Coleman, Novie; Tulloch-Reid, Marshall K; Sacks, Frank M

doi:10.1186/1743-7075-10-73

Table 4 Random effects model to determine influence of apoproteins along with time ¹ , race ² , VAT and insulin resistance on TG levels

From: ApoC-III and visceral adipose tissue contribute to paradoxically normal triglyceride levels in insulin-resistant African-American women

	TG – Light VLDL				TG – Dense VLDL				TG – IDL				TG – LDL
Model	Variables	β-coef	SE	P-val	Variables	β-coef	SE	P-val	Variables	β-coef	SE	P-val	Variables	β-coef	SE	P-val
			R ² =61%				R ² =55%				R ² =27%				R ² =29%
	Race	-0.52	0.25	0.04	Race	-0.21	0.25	0.41	Race	0.04	0.21	0.84	Race	0.02	0.18	0.90
A	S _I ³	-0.09	0.05	0.11	S _I	<0.01	0.05	0.98	S _I	-0.02	0.05	0.68	S _I	- 0.06	0.04	0.13
	VAT	0.46	0.13	<0.01	VAT	0.35	0.12	<0.01	VAT	0.12	0.10	0.23	VAT	- 0.10	0.09	0.28
	ApoB	0.16	0.05	<0.01	ApoB	0.31	0.10	<0.01	ApoB	0.06	0.03	0.04	ApoB	0.01	0.01	<0.01
			R ² =63%				R ² =60%				R ² =42%				R ² =11%
	Race	-0.69	0.23	<0.01	Race	-0.13	0.23	0.59	Race	0.13	0.19	0.48	Race	- 0.09	0.20	0.63
B	S _I	-0.08	0.05	0.12	S _I	-0.01	0.05	0.81	S _I	0.01	0.04	0.75	S _I	- 0.06	0.04	0.14
	VAT	0.47	0.12	<0.01	VAT	0.37	0.11	<0.01	VAT	0.10	0.09	0.27	VAT	- 0.03	0.10	0.79
	ApoCIII	0.37	0.09	<0.01	ApoCIII	0.61	0.15	<0.01	ApoCIII	1.10	0.31	<0.01	ApoCIII	0.07	0.12	0.58
			R ² =58%			R ² =67%					R ² =35%				R ² =12%
	Race	-0.88	0.26	<0.01	Race	-0.36	0.19	0.05	Race	-0.09	0.19	0.62	Race	-0.03	0.21	0.90
C	S _I	-0.09	0.06	0.11	S _I	-0.02	0.04	0.71	S _I	-0.05	0.04	0.27	S _I	-0.06	0.04	0.15
	VAT	0.56	0.13	<0.01	VAT	0.43	0.09	<0.01	VAT	0.08	0.10	0.42	VAT	< 0.01	0.10	0.94
	ApoE	0.57	0.21	<0.01	ApoE	1.72	0.31	<0.01	ApoE	1.03	0.36	<0.01	ApoE	-0.09	0.10	0.39
			R ² =66%				R ² =72%				R ² =49%				R ² =34%
	Race	-0.38	0.26	0.15	Race	0.01	0.19	0.97	Race	0.10	0.18	0.58	Race	0.12	0.19	0.53
D	S _I	-0.04	0.05	0.48	S _I	0.04	0.04	0.31	S _I	<0.01	0.04	0.96	S _I	- 0.05	0.04	0.21
	VAT	0.36	0.13	<0.01	VAT	0.33	0.09	<0.01	VAT	0.04	0.09	0.65	VAT	- 0.07	0.09	0.44
	ApoB	0.12	0.05	0.02	ApoB	0.13	0.08	0.12	ApoB	0.04	0.02	0.13	ApoB	0.02	0.01	< 0.01
	ApoCIII	0.18	0.04	<0.01	ApoCIII	0.27	0.05	<0.01	ApoCIII	0.42	0.15	<0.01	ApoCIII	0.02	0.03	0.59
	ApoE	0.08	0.22	0.72	ApoE	1.07	0.33	<0.01	ApoE	0.73	0.33	0.03	ApoE	-0.13	0.09	0.16

¹Time is significant in every model (P < 0.01).
²Whites are the referent group.
³S_I: Insulin sensitivity index.
The overall R² for each model is presented.

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