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Table 2 Iron status and markers of inflammation in serum between cases and controls

From: Systemic and tumor level iron regulation in men with colorectal cancer: a case control study

 

Cases (n = 20)

Controls (n = 20)

P-value*

Hb (g/dL) †

11.7 (2.9)

13.2 (1.3)

0.01

sTfR (nmol/L) †

21.6 (17.0)

11.8 (6.1)

0.01

Hepcidin (ng/mL) †

58.6 (62.1)

96.0 (34.1)

0.10

CRP (μg/mL)

8.3 (3.4)

3.4 (4.7)

0.002

IL-6 (pg/mL)

2.7 (2.2)

1.9 (1.3)

0.06

TNF-α (pg/mL)

0.32 (0.27)

0.24 (0.36)

0.62

  1. Values shown as median (IQR).
  2. *p-value of difference between cases and controls using Wilcoxon signed-rank test.
  3. †Reference range for healthy men[9]. Hb, 13.5-17.5 g/dL; sTfR, 8.7-28.1 ng/mL; Hepcidin, 29–254 ng/mL.
  4. Hb, hemoglobin; sTfR, serum transferrin receptor; CRP, c-reactive protein; IL-6, interleukin-6; TNF-α, tumor necrosis factor-alpha.