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Table 4 Iron status and markers of inflammation in serum between cases with colonic iron presence (+) and without iron presence (-)

From: Systemic and tumor level iron regulation in men with colorectal cancer: a case control study

 

Iron (+)

Iron (-)

P-value*

P-value†

(n = 6)

(n = 14)

  

Hb (g/dL)

12.8 (2.0)

11.2 (3.4)

0.20

-

sTfR (nmol/L)

11.0 (14.3)

22.2 (18.0)

0.11

0.32

Hepcidin (ng/mL)

80.8 (28.6)

22.0 (48.4)

0.02

0.12

CRP (μg/mL)

7.7 (3.4)

7.9 (3.4)

0.43

0.31

IL-6 (pg/mL)

2.5 (3.0)

2.7 (2.0)

0.99

0.86

TNF-α (pg/mL)

0.27 (0.3)

0.38 (0.3)

0.46

0.41

  1. Values shown as median (IQR).
  2. *p-value of difference between iron(+) and iron (-) using non-parametric Mann–Whitney U test.
  3. †p-value of difference between iron(+) and iron (-) adjusting for Hb with multiple linear regression.
  4. Hb, hemoglobin; sTfR, serum transferrin receptor; CRP, c-reactive protein; IL-6, interleukin-6; TNF-α, tumor necrosis factor-alpha.