Association between prehypertension, metabolic and inflammatory markers, decreased adiponectin and enhanced insulinemia in obese subjects

Table 3 The table shows the circulating plasma concentrations of TNF-α, IL-6 and C-reactive protein, measured in basal period in obese and lean subjects

	Control	n	Normoinsulinemic	n	Hyperinsulinemic	n	P	P¹	P²	P³
	(LS)		(NI)		(HI)			LSvs. NI	LSvs. HI	NIvs. HI
TNF-α (pg/ml)	1.62 ± 0.40	12	2.13 ± 0.60	15	2.01 ± 0.51	12	0.012	0.005	0.028	ns
IL-6 (pg/ml)	0.90 ± 0.38	12	1.97 ± 1.10	15	1.95 ± 0.96	12	0.001	0.001	0.001	ns
CRP (mg/l)	1.56 ± 2.25	12	5.56 ± 4.89	15	6.37 ± 6.70	12	0.025	0.006	ns	ns
Adiponectin (μg/ml)	7.64 ± 2.94	12	8.91 ± 3.39	15	6.32 ± 2.49	12	ns	ns	ns	0.040
Leptin (μg/ml)	11.99 ± 10.63	12	40.70 ± 21.54	15	33.51 ± 21.82	12	0.006	0.002	0.018	ns

TNF-α - tumor necrosis factor-alpha; IL-6 – interleukin 6; CRP – C reactive protein; Values are means ± DP; P values for comparison between groups by non-parametric analysis of Kruskal Wallis; P, comparing all groups: P¹, P² and P³ comparison between groups.

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