Effects of dietary Res treatment on Sirt1, p-AMPK,AMPK, p-FOXO1, FOXO1 protein expressions in liver tissues. (A) Sirt1, p-AMPK, AMPK, p-FOXO1, and FOXO1 protein expressions were measured by Western blotting, each blot stands for at least three independent samples. (B, C, D) Quantitative analysis of expression levels, which was normalized for GAPDH. Data are shown as the mean ± S.D. ##P < 0.01 vs. C57BL/6 J. **P < 0.01 vs. KKAy control, n = 10.