|
Gene1
|
Group2
|
Gene expression3
|
|---|
| | |
Distal ileum
|
Proximal colon
|
|---|
|
ffar2
|
CELL
|
1.16 (0.12-5.16)
|
1.24 (0.20-3.14)
|
| |
FOS
|
2.15 (0.73-7.05)**
|
1.02 (0.33-3.10)
|
| |
GLUC
|
1.07 (0.33-3.81)
|
1.07 (0.43-2.97)
|
| |
PECT
|
1.23 (0.42-7.31)
|
0.63 (0.13-2.48)
|
|
ffar3
|
CELL
|
1.40 (0.15-14.72)
|
0.68 (0.14-3.58)
|
| |
FOS
|
1.11 (0.21-9.44)
|
0.42 (0.06-2.39)*
|
| |
GLUC
|
0.49 (0.02-4.91)
|
0.63 (0.10-7.68)
|
| |
PECT
|
1.15 (0.13-11.39)
|
0.42 (0.09-1.85)**
|
|
sucnr1
|
CELL
|
3.59 (0.17-33.62)*
|
4.13 (0.47-52.44)**
|
| |
FOS
|
0.70 (0.03-11.53)
|
0.82 (0.06-8.85)
|
| |
GLUC
|
1.75 (0.06-23.59)
|
1.65 (0.11-56.72)
|
| |
PECT
|
0.95 (0.01-16.54)
|
0.79 (0.04-14.45)
|
|
GLP-1
|
CELL
|
0.81 (0.34-2.01)
|
0.71 (0.13-4.48)
|
| |
FOS
|
0.79 (0.23-1.93)
|
1.54 (0.35-9.73)
|
| |
GLUC
|
0.78 (0.35-1.69)
|
1.82 (0.43-10.01)
|
| |
PECT
|
0.53 (0.03-1.71)*
|
1.18 (0.15-8.77)
|
|
PYY
|
CELL
|
0.97 (0.46-2.50)
|
0.62 (0.30-1.32)*
|
| |
FOS
|
0.91 (0.24-2.74)
|
0.78 (0.32-3.71)
|
| |
GLUC
|
0.79 (0.32-2.16)
|
1.11 (0.30-3.18)
|
| |
PECT
|
0.40 (0.00-1.75)*
|
0.71 (0.11-2.70)
|
- 1Abbreviations are: ffar free fatty acid receptor, sucnr succinate receptor, GLP-1 glucagon-like peptide-1, PYY peptide tyrosine tyrosine.
- 2Groups were given diets containing 10% w/w fibre as cellulose (CELL), fructo-oligosaccharide (FOS), oat beta-glucan (GLUC) or apple pectin (PECT); n = 10/group.
- 3Values are medians (with 95% C.I.) as determined by REST-2009[32]. *P < 0.05, **P < 0.01.
