Characterization of allantoin induced actions in Min 6 cells. Changes in calcium influx by glibenclamide or allantoin were determined in Min 6 cells (A). The effect of KU14R on allantoin induced insulin secretion (B). All of the values are expressed as the mean ± SEM (n = 6 per group). **P < 0.01 and ***P < 0.001 compared with the control group.