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Figure 4 | Nutrition & Metabolism

Figure 4

From: Allantoin activates imidazoline I-3 receptors to enhance insulin secretion in pancreatic β-cells

Figure 4

Effects of I-3R blockade on allantoin-induced insulin secretion and blood glucose reduction in Wistar rats. Data show the effects of an I-3R antagonist (KU14R) on allantoin-induced blood glucose reduction (A) and insulin secretion (B) in Wistar rats. Values are expressed as the mean and SEM from each group of eight rats. Vehicle (0.9% NaCl in distilled water) was given at the same volume. *P < 0.05 and **P < 0.01 versus data from the vehicle-treated control.

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