Table 5 Proposed beneficiary and detrimental effects of CLA from clinical studies
From: Pros and cons of CLA consumption: an insight from clinical evidences
| Diseases | Positive effects | Negative effects |
|---|---|---|
| Obesity | Reduced body fat mass | Oxidative stress |
| Reduced body mass index | Abdominal irritations | |
| Reduced body fat percentage | ||
| Reduced body fat regain | ||
| Increased lean body mass | ||
| Improved muscle mass | ||
| Cardiovascular diseases | Improved blood lipid profile | Enhanced production of circulatory markers of oxidative stress |
| Reduced total cholesterol | ||
| Immune disorders | Enhanced the levels of protective antibodies | Elevated levels of inflammatory markers in circulation |
| Induced lymphocyte proliferation | ||
| Reduced delayed hypersensitivity responses | ||
| Cancer | Reduced the risks of colorectal, testicular and breast cancers | Increased oxidative stress |
| Diabetes | Enhanced insulin sensitivity | Dysregulation of blood glucose and insulin |
| Insulin resistance | ||
| Decreased expression of GLUT4 |