HFF Day 15 n = 24 | Vehicle n = 4 | 5 mg/kg BW (b.i.d.) n = 4 | 10 mg/kg BW (b.i.d.) n = 4 | 20 mg/kg BW (b.i.d.) n = 4 | 50 mg/kg BW (b.i.d.) n = 4 | 50 mg/kg BW (q.d.) n = 4 | |
---|---|---|---|---|---|---|---|
Weight (g) | 301 ± 2.3 | 312 ± 8a | 312 ± 7a | 312 ± 5d | 310 ± 5a | 316 ± 6b | 317 ± 6c |
Glucose (mg/dl) | 116.0 ± 1.6 | 113.0 ± 3.4 | 113.8 ± 6.4 | 115.3 ± 5.1 | 112.8 ± 2.9 | 115.5 ± 8.7 | 119.3 ± 7.0 |
Insulin (ng/ml) | 1.84 ± 0.06 | 1.78 ± 0.13 | 1.83 ± 0.13 | 1.86 ± 0.15 | 1.77 ± 0.09 | 1.82 ± 0.05 | 1.81 ± 0.13 |
FFA (μEq/l) | 532 ± 17 | 553 ± 54 | 552 ± 63 | 543 ± 92 | 528 ± 32 | 562 ± 39 | 540 ± 52 |
Cholesterol (mg/dl) | 109.6 ± 1.5 | 106.8 ± 5.8 | 109.5 ± 6.4 | 105.0 ± 3.5 | 107.8 ± 2.8 | 109.0 ± 4.1 | 113.3 ± 3.2 |
TG (mg/dl) | 367 ± 16 | 351 ± 31 | 319 ± 59 | 268 ± 18 | 216 ± 17a | 154 ± 33a | 215 ± 39a |