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Table 5 Ratio of RANKL/OPG in Osteoclasts and Osteoblasts in Rats on 50% NR Mg Diet

From: Immunolocalization of RANKL is Increased and OPG Decreased During Dietary Magnesium Deficiency in the Rat

 

50% NR

 

Osteoclast

Osteoblast

3 Month Control

0.24

0.12

3 Month 25% NR

0.30

0.42

6 Month Control

0.13

0.02

6 Month 50% NR

3.13

0.32

  1. As shown in Table 5, the ratio of RANKL to OPG was increased in Mg deficient animals relative to controls in both cell types which favors osteoclastogenesis.