From: Prevalence, predisposition and prevention of type II diabetes
Type 2 diabetes | Â | Â |
---|---|---|
Mutations | Gene Names | Reference |
ABCG8 | ATP-binding cassette Subunit C | [97, 98] |
CAPN10 | Calpain 10 | [99, 100] |
GCGR | Glucagon receptor | [101] |
GCK | Glucokinase | [102] |
KCNJ11 | Potassium channel subunit J, member 11 | [103] |
PPARG | Peroxisome proliferator-activated receptor γ | [104] |
HNF4A | Hepatocyte nuclear factor 4α | [105] |
HNF1A | Hepatocyte nuclear factor 1α | [106] |
SLC2A1 | Glut 1 | [107] |
INS | Insulin | [108] |
INSR | Insulin receptor | [109, 110] |
Mitochondrial genome | Mitochondrial DNA | [111] |
Obesity | Â | Â |
Diabetes | Leptin receptor | [112] |
Mc4r | Melanocortin-4 receptor | [113] |
Obese | Leptin | [114] |
PCSK1 | Prohormone convertase 1 | [115] |
Pomc | Pro-opiomelanocortin | [116] |
SLC6A14 | Solute carrier family 6 member 14 | [117] |