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Table 4 Serum test results (n = 21)

From: A low-carbohydrate, ketogenic diet to treat type 2 diabetes

Measurement

Week 0

Mean (SD)

Week 16

Mean (SD)

Change

%

p value*

Hemoglobin A1c, %

7.5 (1.4)

6.3 (1.0)

-16.0

<0.001

Glucose, mmol/L

9.08 (4.09)

7.57 (2.63)

-16.6

0.04

Total cholesterol, mmol/L

4.61 (1.40)

4.54 (1.26)

-1.5

0.7

Triglyceride, mmol/L

2.69 (2.87)

1.57 (1.38)

-41.6

0.001

HDL-C, mmol/L

0.92 (0.20)

0.99 (0.22)

7.6

0.08

LDL-C, mmol/L

2.51 (0.64)

2.77 (0.89)

10.4

0.1

Sodium, mmol/L

138.2 (3.4)

140.2 (3.4)

1.4

0.02

Potassium, mmol/L

4.2 (0.4)

4.2 (0.3)

0

0.2

Chloride, mmol/L

101.0 (3.4)

103.8 (2.8)

2.8

0.001

Bicarbonate, mmol/L

28.8 (2.0)

28.2 (2.5)

-2.1

0.3

Urea nitrogen, mg/dL

5.90 (1.90)

6.27 (1.81)

6.3

0.3

Creatinine, μmol/L

82.8 (20.4)

79.9 (19.1)

-3.5

0.3

Calcium, mmol/L

2.32 (0.11)

2.33 (0.08)

0.4

0.8

Uric acid, μmol/L

403.5 (94.6)

352.1 (85.4)

-10.3

0.01

TSH, mIU/L

1.6 (1.0)

1.4 (0.7)

-12.7

0.2

Hemoglobin, g/L

142 (11)

141 (10)

-0.7

0.8

  1. Legend: TSH = thyroid-stimulating hormone, HDL-C = high-density lipoprotein cholesterol, LDL-C = low-density lipoprotein cholesterol.
  2. * By paired t-test or Wilcoxon signed-ranks test.
  3. Serum calcium, TSH, total cholesterol, triglyceride, and HDL-C results are based on n of 20 because one participant did not have these tests at baseline. Uric acid is based on n of 19. LDL-C is based on n of 17 because triglyceride levels were too high at baseline to calculate LDL-C in 3 participants.