Thyroid status influence on adiponectin, acylation stimulating protein (ASP) and complement C3 in hyperthyroid and hypothyroid subjects

Table 1 Clinical and laboratory data in subject groups

Parameter	CTL	HYPER	HYPO	ANOVA
N	30	46	23
Gender (M/F)	10/20	13/33	5/18	ns
Age (years)	41.7 ± 2.0	34.9 ± 1.6*	39.4 ± 2.5	0.029
BMI (kg/m²)	22.0 ± 0.4	21.2 ± 0.4^†††	24.2 ± 0.61*	0.0003
Glucose (mmol/L)	4.88 ± 0.11	5.47 ± 0.07***	5.08 ± 0.12^†	<0.0001
Insulin (pmol/L)	34.0 ± 5.5	60.8 ± 4.9***	33.8 ± 2.8^††	<0.0001
HOMA-IR	1.10 ± 0.20	1.86 ± 0.16**	1.02 ± 0.11^††	0.0004
FT4 (pmol/L)	17.4 ± 0.4	64.5 ± 8.4***	9.1 ± 0.6*^†††	<0.0001
FT3 (pmol/L)	5.7 ± 0.1	13.3 ± 1.2***	3.2 ± 0.2**^†††	<0.0001
TSH (mU/L)	2.1 ± 0.1	0.03 ± 0.02***	69.5 ± 21.1**^†††	<0.0001

Results are expressed as average ± SEM for the groups indicated as control (CTL), hyperthyroid (HYPER) and hypothyroid (HYPO) where N = number of subjects per group. Significance was calculated by ANOVA with Bonferroni post-hoc test. Differences vs. control (CTL) group are indicated as *P < 0.05,**P < 0.01,***P < 0.001; and differences for hyperthyroid vs. hypothyroid as ^†p < 0.05, ^††p < 0.01, ^†††p < 0.001, ns = not significant.

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