Table 2 Observational Studies of Stearic Acid and Cardiovascular Outcomes
From: Chocolate and Prevention of Cardiovascular Disease: A Systematic Review
Author | Year | Study design | N, Population | Stearic acid assessment method | CHD/MI Outcomes | Other |
|---|---|---|---|---|---|---|
Kromhout [141] | 1995 | Ecologic | 12,763 men, 16 cohorts of 7CS | Dietary intake | ↑ CHD mortality |  |
Simon [68, 69] | 1995 | Prospective | 96 cases, 96 controls, USA-MRFIT | Serum levels | ↑ CHD incidence | Null-stroke incidence |
Watts [67] | 1996 | Prospective | 50 men, Australia | Dietary intake | ↑ CAD progression |  |
Hojo [61] | 1998 | Case-control | 71 cases, 60 controls, Japan | Serum levels | Â | Null-stenosis |
Hu [65] | 1999 | Prospective | 80,082 women, USA-nurses | Dietary intake | ↑ CHD incidence |  |
Yli-Jama [62] | 2002 | Case-control | 103 cases, 104 controls, Norway | Serum levels | ↓ MI incidence |  |
Kabagambe [63] | 2003 | Case-control | 485 cases, 508 controls, Costa Rica | Dietary intake | ↑ MI incidence |  |
Wang [66] | 2003 | Prospective | 3591 whites, USA | Serum levels | ↑ CHD mortality |  |