Table 2 Effects of 12 wk α-tocopherol supplementation (E+) or restriction (E-) on phylloquinone and MK-4 concentrations in plasma and tissue of rats^1,2,3

E+ (100 mg all-rac-α-tocopherol)

Control (30 mg all-rac-α-tocopherol)

E- (<10 mg total tocopherol)

P

E+ (100 mg all-rac-α-tocopherol)

Control (30 mg all-rac-α-tocopherol)

E- (<10 mg total tocopherol)

P

n = 10

n = 13

n = 10

n = 10

n = 13

n = 10

7.4 ± 0.7^a

10.6 ± 0.8^b

8.7 ± 0.9^a

0.03

0.1 ± 0.3^a

1.7 ± 0.7^b

0.36 ± 0.1^b

0.04

670 ± 79^a

698 ± 41^a

643 ± 91^a

0.86

ND⁴

0.9 ± 0.9

ND⁴

0.50

531 ± 58^a

531 ± 48^a

735 ± 77^b

0.04

163 ± 30^a

133 ± 19^a

153 ± 29^a

0.69