Figure 2
From: Characterization of a monoclonal antibody with specificity for holo-transcobalamin
The mAb 3C4 phagotope CS1-9p and the location of the corresponding putative epitope P40 – Y55 in the simulated three-dimensional model of TC. (epitope 6, red). The epitope clusters identified in [15] are also shown. Epitope clusters 1 (pink), 2 (orange), 3 (magenta), 4 (green), 5 (yellow), and heparin-binding site (blue). The putative cobalamin-binding region is also indicated.