Table 4 Binding of phagemids to mAb 3C4 and blocking by holoTC.
From: Characterization of a monoclonal antibody with specificity for holo-transcobalamin
Phagemid | No. of clones | Sequence | Phage bound (RU) | HoloTC IC50 (μM) |
|---|---|---|---|---|
CS1-2p | 1 | csLFYLWDQDRcs | 4 | - |
CS1-6p | 10 | csFRYLWDQDRcs | 24 | 0.4 |
CS1-9p | 10 | csGLYPWDMFRcs | 35 | 0.3 |
CS1-11p | 10 | csFRYQWDMFRcs | 32 | 0.2 |
CS1-29p | 1 | csFFYSLCYCWcs | 20 | 0.3 |
CS1-31p | 2 | csGLYPWDYFMcs | 42 | 0.3 |
CS1-37p | 1 | csARYSWDRLRcs | 0 | - |