Effect of AICAR on body weight and epididymal fat content in STD and diet induced obesity mice model. C57B6 mice were kept on standard (STD) or 60% fat diet (DIO) treated with AICAR (0.1 or 0.5 mg/g body weight) or PBS for 6 weeks intraperitoneally. Body weight of these mice with AICAR was measured periodically (a). At the indicated time periods, epididymal fat was isolated and weighed (b). Results are shown as mean ± SD of 10 mice.