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Table 3 Levels of some selected serum fatty acids (g/L) at baseline and after 36 months, in the placebo (corn oil) and the n-3 PUFA supplemented groups. Median values (25, 75 percentiles) are given.

From: Effect of diet and omega-3 fatty acid intervention on asymmetric dimethylarginine

 

placebo (corn oil)

n-3 PUFA

 

Baseline (n = 139)

36 Months (n = 114)

Baseline (n = 139)

36 Months (n = 122)

p

Linoleic acid, 18:2n-6

1.59 (1.33, 1.82)

1.58 (1.36, 1.81)

1.70 (1.47, 1.96)

1.47 (1.24, 1.70)b

<0,001

AA, 20:4n-6

0.23 (0.20, 0.27)

0.25 (0.21, 0.30)b

0.22 (0.19, 0.27)

0.21 (0.18, 0.25)b

<0,001

ALA, 18:3n-3

0.030 (0.022, 0. 39)

0.031 (0.024, 0.037)

0.033 (0.026, 0.043)

0.031 (0.025, 0.042)

ns

EPA, 20:5n-3

0.076 (0.049, 0.13)

0.070 (0.041, 0.11)a

0.081 (0.051, 0.14)

0.22 (0.17, 0.27)b

<0,001

DHA, 22:6n-3

0.14 (0.12, 0.19)

0.14 (0.11, 0.18)

0.17 (0.12, 0.20)

0.20 (0.16, 0.23)b

<0,001

Sum n-6

1.82 (1.57, 2.11)

1.86 (1.58, 2.06)

1.94 (1.68, 2.22)

1.68 (1.44, 1.94)b

<0,001

Sum n-3

0.27 (0.20, 0.38)

0.26 (0.21, 0.35)

0.31 (0.22, 0.41)

0.49 (0.39, 0.57)b

<0,001

Ratio omega-6/omega-3

6.85 (4.75, 9.27)

7.08 (5.35, 9.44)

6.36 (4.70, 8.37)

3.40 (2.69, 4.28)b

<0,001

Total fatty acids in serum

5.31 (4.58, 6.22)

5.04 (4.40, 5.70)

5.29 (4.60, 6.25)

4.73 (4.05, 5.59)b

0.011

  1. AA: Arachidonic acid, ALA: Alphalinolenic acid, EPA: Eicosapentaenoic acid, DHA: Docosahexaenoic acid.
  2. a p < 0.05, b p < 0.01 refer to within group changes from baseline to 36 months
  3. p: refers to differences in changes from baseline to 36 months between the group