Figure 6
From: Incorporating genome-scale tools for studying energy homeostasis
Combinatorial siRNA screening strategy for 15 genes. Using this approach the primary effects of a single gene could be discovered using a limited number of experiments. In this case cells were exposed to groups of siRNAs, as opposed to individual sequences. In this example, siRNA groups highlighted in gray have the primary effect on the phenotype, which can be mapped down to the single gene, either gene B or gene C, using a binary search.