Plasma glucose and insulin response (mean ± SEM) for 3 h 75 g oral glucose tolerance test (GTT) by dietary treatment1. 1Mean (± SEM) plasma glucose and insulin concentrations at baseline and 30, 60, 120 and 180 minutes and total AUC after the ingestion of the 75 g oral glucose drink at weeks 0 and 12. The main effect of diet was compared using repeated-measures ANOVA with week and blood sampling time as within subject factors, and diet as between subject factors. The main effect of time (weight loss) for each diet was compared using repeated-measures ANOVA with AUC at week 1 and 12 as within subject factors. * VLCARB significantly different overall from VLF and HUF at week 0 and week 12, P < 0.01. a = no significant effect of weight loss within diet group. b = significant effect of weight loss within diet group (P < 0.05). VLCARB = very low carbohydrate diet (n = 24) VLF = very low fat diet (n = 22) HUF = high unsaturated fat (n = 21).