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Table 3 MC4R mRNA and protein expression and MC3R mRNA expression in CNS regions involved in appetite regulation. Potential targets for POMC and AgRP neurones (references indicated numerically).

From: The role of proopiomelanocortin (POMC) neurones in feeding behaviour

MCR locations:

MC4R mRNA

MC4R GFP expression

MC3R mRNA

Arcuate nucleus

90

105

93, 114, 118

Brainstem

90

105

-

PVN

90, 93

105

118

Lateral hypothalamus

90

105

118

DMH

90

105

118

SON

90

-

-

VMH

90

105

118

Periventricular nucleus

90

105

118

Nucleus accumbens

90

105

-

Amygdala

90

105

118