Treatment | Non-diabetic | Diabetic | ||||||
---|---|---|---|---|---|---|---|---|
Diet | C | WR | BR | PR | C | WR | BR | PR |
Group | C | WR | BR | PR | DC | DWR | DBR | DPR |
Number of animals | 4 | 6 | 6 | 6 | 4 | 9 | 9 | 9 |
Weight (g) | 373.8 ± 7.8 | 374.7 ± 3.8 | 370.3 ± 9.1 | 384.8 ± 13.5 | 174.0 ± 8.6 | 174.2 ± 4.8 | 183.9 ± 2.7 b | 209.0 ± 3.3 a* |
Glucose (mg/dl) | 127.0 ± 1.8 | 135.5 ± 2.7 | 129.0 ± 3.3 | 126.7 ± 4.0 | 438.0 ± 11.0 | 431.0 ± 9.3 | 405.2 ± 9.1 | 351.9 ± 6.3 a* |
NCV (m/s) | 50.4 ± 0.8 | 49.9 ± 1.3 | 50.2 ± 0.8 | 50.4 ± 0.9 | 34.0 ± 1.4 | 34.4 ± 0.8 | 37.9 ± 1.1 | 44.5 ± 1.3 a* |
Na+/K+- ATPase (μmol/g/h) | 6102.5 ± 218.9 | 4855 ± 463.4 | 6998 ± 515.6 | 6302 ± 371.5 | 2238 ± 102 | 2229.3 ± 153.0 | 2437.2 ± 189.9 | 3867.8 ± 177.6 a* |
Homocysteine (μM) | 6.3 ± 0.3 | 5.9 ± 0.1 | 6.1 ± 0.2 | 6.3 ± 0.2 | 3.3 ± 0.2 | 3.1 ± 0.2 | 4.2 ± 0.1 b* | 5.3 ± 0.1 a* |
PON 1 (nmol/ml/min) | 224.0 ± 11.1 | 217.9 ± 4.4 | 216.0 ± 4.6 | 239.5 ± 6.5 | 118.4 ± 7.4 | 117.4 ± 5.9 | 158.3 ± 8.4 a | 187.7 ± 13.6 a* |
HTase (nmol/mg/min) | 9.8 ± 0.4 | 10.0 ± 0.2 | 10.2 ± 0.3 | 10.3 ± 0.3 | 2.0 ± 0.3 c | 1.8 ± 0.2 c | 4.3 ± 0.2 b** | 8.9 ± 0.2 a** |
Creatinine (μmol/l) | 67.3 ± 1.7 | 60.3 ± 1.6 | 59.7 ± 1.3 a* | 59.5 ± 1.0 a* | 89.3 ± 1.7 | 88.3 ± 1.1 a | 82.5 ± 1.3 b* | 72.8 ± 1.1 c* |