Skip to main content

Advertisement

Table 2 Final body weights, blood glucosse concentrations, and peripheral nerve or serum parameters in non-diabetic and diabetic rats (3 weeks) sacrificed at the end of the diet-feeding experiment

From: Effect of pre-germinated brown rice intake on diabetic neuropathy in streptozotocin-induced diabetic rats

Treatment Non-diabetic Diabetic
Diet C WR BR PR C WR BR PR
Group C WR BR PR DC DWR DBR DPR
Number of animals 4 6 6 6 4 9 9 9
Weight (g) 373.8 ± 7.8 374.7 ± 3.8 370.3 ± 9.1 384.8 ± 13.5 174.0 ± 8.6 174.2 ± 4.8 183.9 ± 2.7 b 209.0 ± 3.3 a*
Glucose (mg/dl) 127.0 ± 1.8 135.5 ± 2.7 129.0 ± 3.3 126.7 ± 4.0 438.0 ± 11.0 431.0 ± 9.3 405.2 ± 9.1 351.9 ± 6.3 a*
NCV (m/s) 50.4 ± 0.8 49.9 ± 1.3 50.2 ± 0.8 50.4 ± 0.9 34.0 ± 1.4 34.4 ± 0.8 37.9 ± 1.1 44.5 ± 1.3 a*
Na+/K+- ATPase (μmol/g/h) 6102.5 ± 218.9 4855 ± 463.4 6998 ± 515.6 6302 ± 371.5 2238 ± 102 2229.3 ± 153.0 2437.2 ± 189.9 3867.8 ± 177.6 a*
Homocysteine (μM) 6.3 ± 0.3 5.9 ± 0.1 6.1 ± 0.2 6.3 ± 0.2 3.3 ± 0.2 3.1 ± 0.2 4.2 ± 0.1 b* 5.3 ± 0.1 a*
PON 1 (nmol/ml/min) 224.0 ± 11.1 217.9 ± 4.4 216.0 ± 4.6 239.5 ± 6.5 118.4 ± 7.4 117.4 ± 5.9 158.3 ± 8.4 a 187.7 ± 13.6 a*
HTase (nmol/mg/min) 9.8 ± 0.4 10.0 ± 0.2 10.2 ± 0.3 10.3 ± 0.3 2.0 ± 0.3 c 1.8 ± 0.2 c 4.3 ± 0.2 b** 8.9 ± 0.2 a**
Creatinine (μmol/l) 67.3 ± 1.7 60.3 ± 1.6 59.7 ± 1.3 a* 59.5 ± 1.0 a* 89.3 ± 1.7 88.3 ± 1.1 a 82.5 ± 1.3 b* 72.8 ± 1.1 c*
  1. One-way ANOVA was performed for 4 groups of non-diabetic treatment or diabetic treatment, followed by Tukey's multiple comparison test (if parametric). Difference vs. control (C group or DC group) was analyzed by Dunnet's multiple comparison test (*P < 0.01, **P,0.001). Kruskal-Wallis test was performed for the groups (if non-parametric) followed by Dunn's multiple comparison test. Values are means ± SEM. a,b,cValues with different superscript letters are significantly different among the same column at P < 0.01.