Figure 8From: Expression of PPARα modifies fatty acid effects on insulin secretion in uncoupling protein-2 knockout miceFatty acid oxidation in islets from WT and UCP2 KO mice. Islets cultured 24 h in control (1% BSA, open bars) or PA (0.4 mM + BSA, closed bars) were incubated with 14C-PA and 2.8 mM glucose for 2 h and the evolved 14CO2 was used to estimate fatty acid oxidation (n = 8 for all). * P < 0.05 comparing UCP2 KO to WT islets.Back to article page