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Table 2 Effect of transilent siRNA PPARα transfection (1.5 μg, overnight) on PPARα expression (relative to β-actin) in islets isolated from UCP2 KO mice and WT mice (compared to the transilent siRNA control vector). Data are expressed as means ± sem (n = 4–7).

From: Expression of PPARα modifies fatty acid effects on insulin secretion in uncoupling protein-2 knockout mice

Groups

Control vector

Transilent PPARα vector

UCP2 KO

0.349 ± 0.136

0.029 ± 0.02

WT

0.242 ± 0.116

0.024 ± 0.007