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Table 1 Effect of diet on weight, BMI, HbA1c and fasting lipids. Sixteen obese patients with type 2 diabetes started at month 0 on a diet with the proportions: 20% carbohydrates, 30% protein and 50% fat. The figures shown are means before, 3, 6, 22 and 44 months after the dietary change.

From: Low-carbohydrate diet in type 2 diabetes: stable improvement of bodyweight and glycemic control during 44 months follow-up

Month

0

3

P*

6

P*

22

44

P*

Weight (kg)

100.6 ± 14.7

91.9 ± 14.7

<0.001

89.2 ± 14.3

<0.001

92.0 ± 14.0

93.1 ± 14.5

<0.001

BMI (kg/m2)

36.1 ± 4.2

33.0 ± 4.5

<0.001

32.0 ± 4.3

<0.001

32.9 ± 3.5

33.4 ± 3.9

<0.001

HbA1c (%)

8.0 ± 1.5

5.9 ± 0.7

<0.001

6.6 ± 1.0

<0.001

6.9 ± 1.1

6.8 ± 1.3

<0.001

Lipids(mmol/l)

        

Tot-Chol.

5.6 ± 1.2

5.8 ± 1.1

0.4

6.1 ± 1.1

0.06

5.7 ± 1.2

5.4 ± 1.0

0.8

HDL-Chol.

1.1 ± 0.2

1.2 ± 0.2

<0.002

1.3 ± 0.2

<0.001

1.3 ± 0.3

1.3 ± 0.2

<0.001

§Triglycerides

1.4 (1;1.8)

1.2(0.8;1,4)

0.01

1.4(0.9;1.7)

0.4

1.4(1.2;1.9)

1.4(1.2–2)

0.9

Chol/HDL

5.4 ± 1.5

5.0 ± 1.5

0.02

5.0 ± 1.7

0.07

4.6 ± 1.6

4.1 ± 0.9

<0.001

§TG/HDL

1.4(0.9;1.7)

1.0(0.6;1.2)

0.003

1.0(0.7;1.5)

0.03

1.3(0.8;1.5)

1.1(0.9;1.7)

0.7

  1. §given as medians with 25 and 75 percentiles. * p values are for differences from baseline.