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Table 2 Genes and SNPs analyzed for associations with percent body fat change profiles for LF and LC groups.

From: Physiogenomic comparison of human fat loss in response to diets restrictive of carbohydrate or fat

Area Pathway Gene Symbol SNP Type
Food Intake Neural galanin GAL rs694066 intron 1
   leptin receptor LEPR rs7602 intron 1 (3' UTR on another gene)
     rs1171276 intron 1 (untranslated)
     rs8179183 exon 12, N656K
   melanocortin 3 receptor MC3R rs6024725 ~10 kb upstream
   neuropeptide Y NPY rs1468271 intron 1
   neuropeptide Y receptor Y5 NPY5R rs11100494 intron 3
     rs6837793 ~9 kb upstream
  Neural/Gut histamine N-methyltransferase HNMT rs1801105 exon 4, I105T
     rs12691940 intron 2
  Gut apolipoprotein A-IV APOA4 rs675 T367S, exon 3
     rs5092 exon 2, T29T
   ghrelin precursor GHRL rs26312 ~1 kb upstream
   lipase, gastric LIPF rs814628 exon 4, A161T
   peptide YY PYY rs1058046 exon 2, R72T
     rs231460 ~1.8 kb upstream
Energy Homeostasis Metabolic Enzyme glycogen synthase kinase 3 beta GSK3B rs4688046 intron 3
     rs334555 intron 1
     rs10934502 intron 2
   glycogen synthase 1 (muscle) GYS1 rs2287754 5' UTR
   glycogen synthase 2 (liver) GYS2 rs1478290 upstream, ~3.5 Kb
     rs2306179 intron 5
     rs10505873 intron 3
   phosphofructokinase, liver PFKL rs2838549 intron 8
   phosphofructokinase, muscle PFKM rs2269935 ~700 bp upstream
   pyruvate kinase, liver and RBC PKLR rs3762272 intron 2
   pyruvate kinase, muscle PKM2 rs2856929 intron 7 (MT)
  Nuclear Signaling retinoic acid receptor, alpha RARA rs4890109 intron 3
     rs9904270 ~7.5 kb upstream
   retinoic acid receptor, beta RARB rs2033447 intron 2 (MT)
     rs1290443 intron 3 (MT)
     rs322695 ~100 kb upstream
   retinoic acid receptor, gamma RARG rs10082776 intron 2 (untranslated)
   retinoid X receptor, alpha RXRA rs4917348 ~100 kbp upstream
     rs3750546 ~100 kb upstream
     rs3118536 intron 3
   retinoid X receptor, gamma RXRG rs157864 intron 4
Adipocyte Regulation Adipokine-related adiponectin receptor 2 ADIPOR2 rs2058112 intron 1 (untranslated?)
     rs7975375 intron 1 (untranslated?)
   angiotensin II receptor, type 1 AGTR1 rs12695902 intron 3
     rs931490 intron 2 (untranslated?), (MT)
   angiotensin II receptor, type 2 AGTR2 rs5950584 ~4.5 kb upstream
   resistin RETN rs3219177 intron 1
  Lipid Metabolic apolipoprotein E APOE rs7412 exon 3, C176R, *2–>*3
     rs429358 exon 3, R130C, *4–>*3
     rs405509 ~200 bp upstream
     rs439401 ~1.5 kbp downstream
     rs446037 ~1.5 kbp upstream
   cholesteryl ester transfer protein, plasma CETP rs5883 exon 9, F287F
     rs1532624 intron 7
     rs3764261 ~2.6 kb upstream
     rs5880 nonsynonymous, P390A