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Table 6 Significance levels of gene SNPs associated with % body fat change profiles for carbohydrate-restricted (LC) and fat-restricted (LF) diet treatments.

From: Physiogenomic comparison of human fat loss in response to diets restrictive of carbohydrate or fat

  Marker P-value Coefficient FDR
Area SNP Gene LF LC LF LC LF LC
Food Intake rs1801105 HNMT 0.941 0.028 -0.03 -2.03 0.960 0.368
  rs12691940 HNMT 0.002 0.755 0.89 -0.12 0.041 0.974
  rs1468271 NPY 0.049 0.181 -0.89 -0.90 0.321 0.974
Energy Homeostasis rs1478290 GYS2 0.038 0.009 -0.60 -0.86 0.321 0.209
  rs2838549 PFKL 0.002 0.902 1.37 -0.10 0.041 0.974
  rs3762272 PKLR 0.048 0.282 -2.24 -0.60 0.321 0.974
  rs322695 RARB 0.0001 0.012 1.29 1.03 0.005 0.209
Adipocyte Regulation rs2058112 ADIPOR2 0.044 0.141 -0.89 -0.78 0.321 0.974
  rs5950584 AGTR2 0.507 0.0001 -0.77 -3.31 0.732 0.021
  rs439401 APOE 0.036 0.691 -0.74 -0.15 0.321 0.974
  1. Abbreviations: Coefficient: linear regression coefficient; FDR: false discovery rate p value, with those in bold type significant at α ≤ 0.05.