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Table 6 Significance levels of gene SNPs associated with % body fat change profiles for carbohydrate-restricted (LC) and fat-restricted (LF) diet treatments.

From: Physiogenomic comparison of human fat loss in response to diets restrictive of carbohydrate or fat

 

Marker

P-value

Coefficient

FDR

Area

SNP

Gene

LF

LC

LF

LC

LF

LC

Food Intake

rs1801105

HNMT

0.941

0.028

-0.03

-2.03

0.960

0.368

 

rs12691940

HNMT

0.002

0.755

0.89

-0.12

0.041

0.974

 

rs1468271

NPY

0.049

0.181

-0.89

-0.90

0.321

0.974

Energy Homeostasis

rs1478290

GYS2

0.038

0.009

-0.60

-0.86

0.321

0.209

 

rs2838549

PFKL

0.002

0.902

1.37

-0.10

0.041

0.974

 

rs3762272

PKLR

0.048

0.282

-2.24

-0.60

0.321

0.974

 

rs322695

RARB

0.0001

0.012

1.29

1.03

0.005

0.209

Adipocyte Regulation

rs2058112

ADIPOR2

0.044

0.141

-0.89

-0.78

0.321

0.974

 

rs5950584

AGTR2

0.507

0.0001

-0.77

-3.31

0.732

0.021

 

rs439401

APOE

0.036

0.691

-0.74

-0.15

0.321

0.974

  1. Abbreviations: Coefficient: linear regression coefficient; FDR: false discovery rate p value, with those in bold type significant at α ≤ 0.05.