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Table 3 Demographic Characteristics by APOE4 status (N)

From: Study of the ketogenic agent AC-1202 in mild to moderate Alzheimer's disease: a randomized, double-blind, placebo-controlled, multicenter trial

 

APOE4(-)

APOE4(+)

p-value*

Mean Age

76.2 (54)

76.5 (68)

0.796

Mean ADAS-Cog

21.9 (59)

23.4 (69)

0.273

Mean MMSE

20.3 (55)

19.4 (70)

0.239

Sex

F 59% (37)

F 53% (38)

 

F = female, M = male

M 41% (26)

M 47% (34)

0.603

Donepezil

N 60% (38)

N 47% (34)

 
 

Y 40% (25)

Y 53% (38)

0.167

Memantine

N 70% (44)

N 50% (36)

0.023

 

Y 30% (19)

Y 50% (36)

 

Galantamine

N 95% (60)

N 92% (66)

0.502

 

Y 5% (3)

Y 8% (6)

 

Number of AD medications

0 – 30% (19)

0 – 15% (11)

 
 

1 – 51% (32)

1 – 44% (32)

 
 

2 – 19% (12)

2 – 40% (29)

0.012†

Completed study

N 37% (23)

N 33% (24)

0.721

 

Y 63% (40)

Y 67% (48)

 
  1. N = no, Y = yes
  2. *Fisher Exact test
  3. †Contingency analysis