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Table 3 Demographic Characteristics by APOE4 status (N)

From: Study of the ketogenic agent AC-1202 in mild to moderate Alzheimer's disease: a randomized, double-blind, placebo-controlled, multicenter trial

  APOE4(-) APOE4(+) p-value*
Mean Age 76.2 (54) 76.5 (68) 0.796
Mean ADAS-Cog 21.9 (59) 23.4 (69) 0.273
Mean MMSE 20.3 (55) 19.4 (70) 0.239
Sex F 59% (37) F 53% (38)  
F = female, M = male M 41% (26) M 47% (34) 0.603
Donepezil N 60% (38) N 47% (34)  
  Y 40% (25) Y 53% (38) 0.167
Memantine N 70% (44) N 50% (36) 0.023
  Y 30% (19) Y 50% (36)  
Galantamine N 95% (60) N 92% (66) 0.502
  Y 5% (3) Y 8% (6)  
Number of AD medications 0 – 30% (19) 0 – 15% (11)  
  1 – 51% (32) 1 – 44% (32)  
  2 – 19% (12) 2 – 40% (29) 0.012
Completed study N 37% (23) N 33% (24) 0.721
  Y 63% (40) Y 67% (48)  
  1. N = no, Y = yes
  2. *Fisher Exact test
  3. Contingency analysis